Definitely seeing your internal hard drive and DVD Rom Drive in the "Safely Remove Hardware" Tab in the taskbar is not normal. I've encounter such situation in my PC when i reformat it. But this doesn't mean it will work to other motherboards.
Operating System: Windows XP (SP2)
Motherboard: Asus Motherboard (P5VD2-X)
HDD: 250GB Seagate (IDE)
ROM Drive: Asus DRW-2014L1
> Restart your computer.
> Enter BIOS CMOS Setup Utility
> Go to Advanced Tab and press Enter
> Go to Onboard Device Configuration and press Enter
> Under Onboard Device Configuration look for "SATA Controller"
> Change option to "Enabled"
> Press F10
> Press Y to confirm changes
Your Internal HDD and DVD Rom Drive should be ok now and it should not appear in the "Safely Remove Hardware" Tab at the Taskbar anymore.